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The Immunomodulatory Effect and Clinical Efficacy of Daratumumab in a Patient With Cold Agglutinin Disease

Daratumumab is a monoclonal antibody directed against the transmembrane glycoprotein CD38 expressed on plasma cells and lymphoplasmocytes, with a proven efficacy in multiple myeloma. Here we show its clinical efficacy in a patient with cold agglutinin disease (CAD) relapsed after multiple lines of t...

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Detalles Bibliográficos
Autores principales: Zaninoni, Anna, Giannotta, Juri A., Gallì, Anna, Artuso, Rosangela, Bianchi, Paola, Malcovati, Luca, Barcellini, Wilma, Fattizzo, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956980/
https://www.ncbi.nlm.nih.gov/pubmed/33732266
http://dx.doi.org/10.3389/fimmu.2021.649441

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