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Inhibition of adenosine kinase attenuates myocardial ischaemia/reperfusion injury
Increased adenosine helps limit infarct size in ischaemia/reperfusion‐injured hearts. In cardiomyocytes, 90% of adenosine is catalysed by adenosine kinase (ADK) and ADK inhibition leads to higher concentrations of both intracellular adenosine and extracellular adenosine. However, the role of ADK inh...
Autores principales: | Wang, Wenjun, Wang, Bailu, Sun, Shukun, Cao, Shengchuan, Zhai, Xiaoxuan, Zhang, Chuanxin, Zhang, Qun, Yuan, Qiuhuan, Sun, Yi, Xue, Mengyang, Ma, Jingjing, Xu, Feng, Wei, Shujian, Chen, Yuguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957171/ https://www.ncbi.nlm.nih.gov/pubmed/33523568 http://dx.doi.org/10.1111/jcmm.16328 |
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