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Distinct immune regulatory receptor profiles linked to altered monocyte subsets in sarcoidosis

BACKGROUND: In sarcoidosis, blood monocytes, circulating precursors of granuloma macrophages, display enhanced inflammatory cytokine production, reduced expression of the regulatory (inhibitory) receptor CD200R, and altered subsets defined by CD14 and CD16. Regulatory receptors serve to dampen monoc...

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Detalles Bibliográficos
Autores principales:	Fraser, Simon D., Crooks, Michael G., Kaye, Paul M., Hart, Simon P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957298/ https://www.ncbi.nlm.nih.gov/pubmed/33748262 http://dx.doi.org/10.1183/23120541.00804-2020

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