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Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells

OBJECTIVE: The purpose of this paper is to investigate the effects of senescent nucleus pulposus cell (NPC)‐derived exosomes (SNPC‐Exo) and the roles of the P53/P21 pathway on the senescence of NPC. METHODS: The senescent phenotypes of NPC were induced by interleukin‐1β treatment. SNPC‐Exo was extra...

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Detalles Bibliográficos
Autores principales:	Chen, Chang‐chun, Chen, Jing, Wang, Wen‐liang, Xie, Liang, Shao, Chuan‐qiang, Zhang, Yan‐xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2020
Materias:	Scientific Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957423/ https://www.ncbi.nlm.nih.gov/pubmed/33314719 http://dx.doi.org/10.1111/os.12886

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