Molecular basis of accessible plasma membrane cholesterol recognition by the GRAM domain of GRAMD1b

Cholesterol is essential for cell physiology. Transport of the “accessible” pool of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) by ER‐localized GRAMD1 proteins (GRAMD1a/1b/1c) contributes to cholesterol homeostasis. However, how cells detect accessible cholesterol wit...

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Detalles Bibliográficos
Autores principales: Ercan, Bilge, Naito, Tomoki, Koh, Dylan Hong Zheng, Dharmawan, Dennis, Saheki, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957428/
https://www.ncbi.nlm.nih.gov/pubmed/33604931
http://dx.doi.org/10.15252/embj.2020106524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957428/
https://www.ncbi.nlm.nih.gov/pubmed/33604931
http://dx.doi.org/10.15252/embj.2020106524

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