Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral Vectors

Adenovirus-based gene transfer vectors are the most frequently used vector type in gene therapy clinical trials to date, and they play an important role as genetic vaccine candidates during the ongoing SARS-CoV-2 pandemic. Immediately upon delivery, adenovirus-based vectors exhibit multiple complex...

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Detalles Bibliográficos
Autores principales: Kreppel, Florian, Hagedorn, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957472/
https://www.ncbi.nlm.nih.gov/pubmed/33670859
http://dx.doi.org/10.3390/ijms22052417

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957472/
https://www.ncbi.nlm.nih.gov/pubmed/33670859
http://dx.doi.org/10.3390/ijms22052417

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