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Capsid and Genome Modification Strategies to Reduce the Immunogenicity of Adenoviral Vectors
Adenovirus-based gene transfer vectors are the most frequently used vector type in gene therapy clinical trials to date, and they play an important role as genetic vaccine candidates during the ongoing SARS-CoV-2 pandemic. Immediately upon delivery, adenovirus-based vectors exhibit multiple complex...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957472/ https://www.ncbi.nlm.nih.gov/pubmed/33670859 http://dx.doi.org/10.3390/ijms22052417 |