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Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H(1) Receptors

The binding affinity of ligands for their receptors is determined by their kinetic and thermodynamic binding properties. Kinetic analyses of the rate constants of association and dissociation (k(on) and k(off), respectively) of antihistamines have suggested that second-generation antihistamines have...

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Detalles Bibliográficos
Autores principales:	Akimoto, Hayato, Uesawa, Yoshihiro, Hishinuma, Shigeru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957501/ https://www.ncbi.nlm.nih.gov/pubmed/33673686 http://dx.doi.org/10.3390/ijms22052400

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