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Fibrinogen Interaction with Astrocyte ICAM-1 and PrP(C) Results in the Generation of ROS and Neuronal Death
Many neuroinflammatory diseases, like traumatic brain injury (TBI), are associated with an elevated level of fibrinogen and short-term memory (STM) impairment. We found that during TBI, extravasated fibrinogen deposited in vasculo-astrocyte interfaces, which was associated with neurodegeneration and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957521/ https://www.ncbi.nlm.nih.gov/pubmed/33673626 http://dx.doi.org/10.3390/ijms22052391 |