Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

SIMPLE SUMMARY: Despite the breakthrough in human cancer immunotherapy, colorectal cancer, except for the small subset of microsatellite instable colorectal cancer (MSI, ~4% total cases), is one of the few human cancers that does not respond to current immune checkpoint inhibitor (ICI) immunotherapy...

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Detalles Bibliográficos
Autores principales: Klement, John D., Poschel, Dakota B., Lu, Chunwan, Merting, Alyssa D., Yang, Dafeng, Redd, Priscilla S., Liu, Kebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957528/
https://www.ncbi.nlm.nih.gov/pubmed/33670921
http://dx.doi.org/10.3390/cancers13051006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957528/
https://www.ncbi.nlm.nih.gov/pubmed/33670921
http://dx.doi.org/10.3390/cancers13051006

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