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A Novel Bispecific Antibody Targeting EGFR and VEGFR2 Is Effective against Triple Negative Breast Cancer via Multiple Mechanisms of Action

SIMPLE SUMMARY: Triple-negative breast cancer (TNBC) accounts for approximately 10–20% of all diagnosed breast cancers and is often associated with a poor prognosis. There is therefore an urgent need to develop novel and targeted therapeutic approaches against TNBC. Epidermal growth factor receptor...

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Detalles Bibliográficos
Autores principales: Mohan, Nishant, Luo, Xiao, Shen, Yi, Olson, Zachary, Agrawal, Atul, Endo, Yukinori, Rotstein, David S., Pelosof, Lorraine C., Wu, Wen Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957537/
https://www.ncbi.nlm.nih.gov/pubmed/33804477
http://dx.doi.org/10.3390/cancers13051027