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Genetic Regulation of Tryptase Production and Clinical Impact: Hereditary Alpha Tryptasemia, Mastocytosis and Beyond

Tryptase is a serine protease that is predominantly produced by tissue mast cells (MCs) and stored in secretory granules together with other pre-formed mediators. MC activation, degranulation and mediator release contribute to various immunological processes, but also to several specific diseases, s...

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Detalles Bibliográficos
Autores principales: Sprinzl, Bettina, Greiner, Georg, Uyanik, Goekhan, Arock, Michel, Haferlach, Torsten, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957558/
https://www.ncbi.nlm.nih.gov/pubmed/33671092
http://dx.doi.org/10.3390/ijms22052458

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