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Genetic Regulation of Tryptase Production and Clinical Impact: Hereditary Alpha Tryptasemia, Mastocytosis and Beyond
Tryptase is a serine protease that is predominantly produced by tissue mast cells (MCs) and stored in secretory granules together with other pre-formed mediators. MC activation, degranulation and mediator release contribute to various immunological processes, but also to several specific diseases, s...
Autores principales: | Sprinzl, Bettina, Greiner, Georg, Uyanik, Goekhan, Arock, Michel, Haferlach, Torsten, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957558/ https://www.ncbi.nlm.nih.gov/pubmed/33671092 http://dx.doi.org/10.3390/ijms22052458 |
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