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Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study

Ultrasound-based shear wave elastography (SWE) provides the means to quantify tissue mechanical properties in vivo and has proven valuable in detecting degenerative processes in tendons. Its current mode of use is for two-dimensional rendering measurements, which are highly position-dependent. We th...

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Autores principales: Götschi, Tobias, Schulz, Nicole, Snedeker, Jess G., Hanimann, Jonas, Franchi, Martino V., Spörri, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957754/
https://www.ncbi.nlm.nih.gov/pubmed/33673664
http://dx.doi.org/10.3390/s21051655
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author Götschi, Tobias
Schulz, Nicole
Snedeker, Jess G.
Hanimann, Jonas
Franchi, Martino V.
Spörri, Jörg
author_facet Götschi, Tobias
Schulz, Nicole
Snedeker, Jess G.
Hanimann, Jonas
Franchi, Martino V.
Spörri, Jörg
author_sort Götschi, Tobias
collection PubMed
description Ultrasound-based shear wave elastography (SWE) provides the means to quantify tissue mechanical properties in vivo and has proven valuable in detecting degenerative processes in tendons. Its current mode of use is for two-dimensional rendering measurements, which are highly position-dependent. We therefore propose an approach to create a volumetric reconstruction of the mechano-acoustic properties of a structure of interest based on optically tracking the ultrasound probe during free-hand measurement sweeps. In the current work, we aimed (1) to assess the technical feasibility of the three-dimensional mapping of unidirectional shear wave velocity (SWV), (2) to evaluate the possible artefacts associated with hand-held image acquisition, (3) to investigate the reproducibility of the proposed technique, and (4) to study the potential of this method in detecting local adaptations in a longitudinal study setting. Operative and technical feasibility as well as potential artefacts associated with hand-held image acquisition were studied on a synthetic phantom containing discrete targets of known mechanical properties. Measurement reproducibility was assessed based on inter-day and inter-reader scans of the patellar, Achilles, and supraspinatus tendon of ten healthy volunteers and was compared to traditional two-dimensional image acquisition. The potential of this method in detecting local adaptations was studied by testing the effect of short-term voluntary isometric loading history on SWV along the tendon long axis. The suggested approach was technically feasible and reproducible, with a moderate to very good reliability and a standard error of measurement in the range of 0.300–0.591 m/s for the three assessed tendons at the two test-retest modalities. We found a consistent variation in SWV along the longitudinal axis of each tendon, and isometric loading resulted in regional increases in SWV in the patellar and Achilles tendons. The proposed method outperforms traditional two-dimensional measurement with regards to reproducibility and may prove valuable in the objective assessment of pathological tendon changes.
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spelling pubmed-79577542021-03-16 Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study Götschi, Tobias Schulz, Nicole Snedeker, Jess G. Hanimann, Jonas Franchi, Martino V. Spörri, Jörg Sensors (Basel) Article Ultrasound-based shear wave elastography (SWE) provides the means to quantify tissue mechanical properties in vivo and has proven valuable in detecting degenerative processes in tendons. Its current mode of use is for two-dimensional rendering measurements, which are highly position-dependent. We therefore propose an approach to create a volumetric reconstruction of the mechano-acoustic properties of a structure of interest based on optically tracking the ultrasound probe during free-hand measurement sweeps. In the current work, we aimed (1) to assess the technical feasibility of the three-dimensional mapping of unidirectional shear wave velocity (SWV), (2) to evaluate the possible artefacts associated with hand-held image acquisition, (3) to investigate the reproducibility of the proposed technique, and (4) to study the potential of this method in detecting local adaptations in a longitudinal study setting. Operative and technical feasibility as well as potential artefacts associated with hand-held image acquisition were studied on a synthetic phantom containing discrete targets of known mechanical properties. Measurement reproducibility was assessed based on inter-day and inter-reader scans of the patellar, Achilles, and supraspinatus tendon of ten healthy volunteers and was compared to traditional two-dimensional image acquisition. The potential of this method in detecting local adaptations was studied by testing the effect of short-term voluntary isometric loading history on SWV along the tendon long axis. The suggested approach was technically feasible and reproducible, with a moderate to very good reliability and a standard error of measurement in the range of 0.300–0.591 m/s for the three assessed tendons at the two test-retest modalities. We found a consistent variation in SWV along the longitudinal axis of each tendon, and isometric loading resulted in regional increases in SWV in the patellar and Achilles tendons. The proposed method outperforms traditional two-dimensional measurement with regards to reproducibility and may prove valuable in the objective assessment of pathological tendon changes. MDPI 2021-02-27 /pmc/articles/PMC7957754/ /pubmed/33673664 http://dx.doi.org/10.3390/s21051655 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Götschi, Tobias
Schulz, Nicole
Snedeker, Jess G.
Hanimann, Jonas
Franchi, Martino V.
Spörri, Jörg
Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title_full Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title_fullStr Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title_full_unstemmed Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title_short Three-Dimensional Mapping of Shear Wave Velocity in Human Tendon: A Proof of Concept Study
title_sort three-dimensional mapping of shear wave velocity in human tendon: a proof of concept study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957754/
https://www.ncbi.nlm.nih.gov/pubmed/33673664
http://dx.doi.org/10.3390/s21051655
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