ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates the importance of the localization of ADAM10 for its act...

Descripción completa

Detalles Bibliográficos
Autores principales: Pereira Vatanabe, Izabela, Peron, Rafaela, Mantellatto Grigoli, Marina, Pelucchi, Silvia, De Cesare, Giulia, Magalhães, Thamires, Manzine, Patricia Regina, Figueredo Balthazar, Marcio Luiz, Di Luca, Monica, Marcello, Elena, Cominetti, Marcia Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957802/
https://www.ncbi.nlm.nih.gov/pubmed/33670873
http://dx.doi.org/10.3390/ijms22052416

Ejemplares similares

Ejemplares similares