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Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation
BACKGROUND & AIMS: Currently, only a few genetic variants explain the heritability of fatty liver disease. Quantitative trait loci (QTL) analysis of mouse strains has identified the susceptibility locus Ltg/NZO (liver triglycerides from New Zealand obese [NZO] alleles) on chromosome 18 as associ...
Autores principales: | Schwerbel, Kristin, Kamitz, Anne, Krahmer, Natalie, Hallahan, Nicole, Jähnert, Markus, Gottmann, Pascal, Lebek, Sandra, Schallschmidt, Tanja, Arends, Danny, Schumacher, Fabian, Kleuser, Burkhard, Haltenhof, Tom, Heyd, Florian, Gancheva, Sofiya, Broman, Karl W., Roden, Michael, Joost, Hans-Georg, Chadt, Alexandra, Al-Hasani, Hadi, Vogel, Heike, Jonas, Wenke, Schümann, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957830/ https://www.ncbi.nlm.nih.gov/pubmed/32376415 http://dx.doi.org/10.1016/j.jhep.2020.04.031 |
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