iTRAQ‐based proteomic analysis of the molecular mechanisms and downstream effects of fatty acid synthase in osteosarcoma cells

BACKGROUND: Fatty acid synthase (FASN) is a lipogenic enzyme that participates in tumor progression. We previously showed that FASN is dysregulated in OS malignancy, but the molecular mechanism(s) of these effects remained unclear. METHODS: We examined differentially expressed proteins (DEPs) in FAS...

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Detalles Bibliográficos
Autores principales: Fu, Dahua, Liu, Shuochuan, Liu, Jiaming, Chen, Wenzhao, Long, Xinhua, Chen, Xuanyin, Zhou, Yang, Zheng, Yibin, Huang, Shanhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957979/
https://www.ncbi.nlm.nih.gov/pubmed/33405298
http://dx.doi.org/10.1002/jcla.23653

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