Cargando…

Prognostic value of BRAF/MIR‐17 signature and B‐Raf protein expression in patients with colorectal cancer: A pilot study

BACKGROUND: Despite the recent improvement in colorectal cancer (CRC) treatment, it still has a poor prognosis with a low survival rate. Genetic and epigenetic mechanisms have proved to play a substantial role in CRC tumorigenesis and progression. According to Gene Ontology and TargetScan analyses,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ibrahiem, Afaf T., Fawzy, Manal S., Abu AlSel, Baraah T., Toraih, Eman A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957984/ https://www.ncbi.nlm.nih.gov/pubmed/33296098 http://dx.doi.org/10.1002/jcla.23679

Ejemplares similares

Analysis of microRNA-34a expression profile and rs2666433 variant in colorectal cancer: a pilot study
por: Fawzy, Manal S., et al.
Publicado: (2020)

Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end‐stage renal disease
por: Fawzy, Manal S., et al.
Publicado: (2020)

Molecular analysis of homeostatic iron regulator, transmembrane protease serine-6, and BTB domain-containing protein-9 variants and iron parameters in blood donors
por: Fawzy, Manal S., et al.
Publicado: (2021)

Assessment of Vitamin D-Binding Protein and Early Prediction of Nephropathy in Type 2 Saudi Diabetic Patients
por: Fawzy, Manal S., et al.
Publicado: (2018)

MicroRNA-499a (rs3746444A/G) gene variant and susceptibility to type 2 diabetes-associated end-stage renal disease
por: Fawzy, Manal S., et al.
Publicado: (2022)

GLUT1 and ASCT2 Protein Expression in Papillary Thyroid Carcinoma Patients and Relation to Hepatitis C Virus: A Propensity-Score Matched Analysis
por: Ibrahiem, Afaf T, et al.
Publicado: (2022)

Prognostic Value of LINC-ROR (rs1942347) Variant in Patients with Colon Cancer Harboring BRAF Mutation: A Propensity Score-Matched Analysis
por: Shaalan, Aly A. M., et al.
Publicado: (2022)

Prognostic Value of BRAF, Programmed Cell Death 1 (PD1), and PD Ligand 1 (PDL1) Protein Expression in Colon Adenocarcinoma
por: Ibrahiem, Afaf T., et al.
Publicado: (2023)

Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study
por: Fawzy, Manal S., et al.
Publicado: (2017)

Association of B‐cell lymphoma 2/microRNA‐497 gene expression ratio score with metastasis in patients with colorectal cancer: A propensity‐matched cohort analysis
por: Kattan, Shahad W., et al.
Publicado: (2022)

MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma
por: Toraih, Eman A., et al.
Publicado: (2017)

Impact of cytotoxic T‐lymphocyte‐associated protein 4 codon 17 variant and expression on vitiligo risk
por: Gouda, Nawal S., et al.
Publicado: (2021)

MicroRNA-17-92a-1 Host Gene (MIR17HG) Expression Signature and rs4284505 Variant Association with Alopecia Areata: A Case–Control Study
por: Faisal, Salwa, et al.
Publicado: (2022)

Analysis of anti‐apoptotic PVT1 oncogene and apoptosis‐related proteins (p53, Bcl2, PD‐1, and PD‐L1) expression in thyroid carcinoma
por: Ibrahiem, Afaf T., et al.
Publicado: (2022)

PUNISHER rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer
por: Shaheen, Sameerah, et al.
Publicado: (2022)

MicroRNA-155 and Disease-Related Immunohistochemical Parameters in Cutaneous Melanoma
por: Fawzy, Manal S., et al.
Publicado: (2023)

Data supporting the structural and functional characterization of Thrombin‐Activatable Fibrinolysis Inhibitor in breast cancer
por: Fawzy, Manal S., et al.
Publicado: (2015)

Analysis of the autoimmune regulator (AIRE) gene variant rs2075876 (G/A) association with breast cancer susceptibility
por: Fawzy, Manal S., et al.
Publicado: (2020)

Deregulated MicroRNA Signature Following Glioblastoma Irradiation
por: Toraih, Eman A., et al.
Publicado: (2019)

RAF inhibitors transactivate RAF dimers and ERK signaling in cells with wild-type BRAF
por: Poulikakos, Poulikos I., et al.
Publicado: (2010)

Mobile phones electromagnetic radiation and NAD(+)-dependent isocitrate dehydrogenase as a mitochondrial marker in asthenozoospermia
por: Hagras, Abeer M., et al.
Publicado: (2016)

Association of MicroRNA-196a2 Variant with Response to Short-Acting β2-Agonist in COPD: An Egyptian Pilot Study
por: Fawzy, Manal S., et al.
Publicado: (2016)

Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer
por: Pan, Jing-hua, et al.
Publicado: (2018)

An amino-terminal BRAF deletion accounting for acquired resistance to RAF/EGFR inhibition in colorectal cancer
por: Tung, Jack K., et al.
Publicado: (2020)

Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma
por: Toraih, Eman A., et al.
Publicado: (2017)

Atherosclerotic and thrombotic genetic and environmental determinants in Egyptian coronary artery disease patients: a pilot study
por: Fawzy, Manal S., et al.
Publicado: (2017)

Association of microRNA 17 host gene variant (rs4284505) with susceptibility and severity of systemic lupus erythematosus
por: Abdel‐Gawad, Abdelhady R., et al.
Publicado: (2020)

Longevity-Related Gene Transcriptomic Signature in Glioblastoma Multiforme
por: Fawzy, Manal S., et al.
Publicado: (2018)

A Review and In Silico Analysis of Tissue and Exosomal Circular RNAs: Opportunities and Challenges in Thyroid Cancer
por: Toraih, Eman A., et al.
Publicado: (2022)

Interactome dynamics of RAF1-BRAF kinase monomers and dimers
por: Iglesias-Martinez, Luis F., et al.
Publicado: (2023)

Dual biomarkers long non-coding RNA GAS5 and microRNA-34a co-expression signature in common solid tumors
por: Toraih, Eman A., et al.
Publicado: (2018)

Circulating long noncoding RNAs H19 and GAS5 are associated with type 2 diabetes but not with diabetic retinopathy: A preliminary study
por: Fawzy, Manal S., et al.
Publicado: (2020)

Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors
por: Chatelle, Claire V., et al.
Publicado: (2016)

BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors
por: Schreck, Karisa C., et al.
Publicado: (2019)

RAF inhibitor PLX8394 selectively disrupts BRAF-dimers and RAS-independent BRAF mutant-driven signaling
por: Yao, Zhan, et al.
Publicado: (2018)

Association of VDBP rs4701 Variant, but not VDR/RXR-α Over-Expression with Bone Mineral Density in Pediatric Well-Chelated β-Thalassemia Patients
por: Sahmoud, Shaimaa, et al.
Publicado: (2020)

Association of microRNA-34a rs2666433 (A/G) Variant with Systemic Lupus Erythematosus in Female Patients: A Case-Control Study
por: Ismail, Nesreen M., et al.
Publicado: (2021)

Antioxidants-Related Superoxide Dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPX), Glutathione-S-Transferase (GST), and Nitric Oxide Synthase (NOS) Gene Variants Analysis in an Obese Population: A Preliminary Case-Control Study
por: Gusti, Amani M. T., et al.
Publicado: (2021)

Type 2 diabetes and thyroid cancer: Synergized risk with rising air pollution
por: Kruger, Eva M, et al.
Publicado: (2023)

Targeting RAF Isoforms and Tumor Microenvironments in RAS or BRAF Mutant Colorectal Cancers with SJ-C1044 for Anti-Tumor Activity
por: Hong, Sungpyo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4u3f2l7vu0ktpv1m7p56lbf9r1