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Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report

BACKGROUND: Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity. CASE PRESENTATION: This...

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Autores principales: Ferry, Thomas, Amiet, Vivianne, Natterer, Julia, Perez, Marie-Hélène, Pfister, Raymond, Colombier, Sébastien, Longchamp, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958095/
https://www.ncbi.nlm.nih.gov/pubmed/33722251
http://dx.doi.org/10.1186/s13049-021-00850-0
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author Ferry, Thomas
Amiet, Vivianne
Natterer, Julia
Perez, Marie-Hélène
Pfister, Raymond
Colombier, Sébastien
Longchamp, David
author_facet Ferry, Thomas
Amiet, Vivianne
Natterer, Julia
Perez, Marie-Hélène
Pfister, Raymond
Colombier, Sébastien
Longchamp, David
author_sort Ferry, Thomas
collection PubMed
description BACKGROUND: Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity. CASE PRESENTATION: This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover. CONCLUSIONS: Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment.
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spelling pubmed-79580952021-03-15 Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report Ferry, Thomas Amiet, Vivianne Natterer, Julia Perez, Marie-Hélène Pfister, Raymond Colombier, Sébastien Longchamp, David Scand J Trauma Resusc Emerg Med Case Report BACKGROUND: Chloroquine use has increased worldwide recently in the setting of experimental treatment for the novel coronavirus disease (Covid-19). Nevertheless, in case of chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its cardiac toxicity. CASE PRESENTATION: This case study reports on a 14-years-old girl who presented in cardiac arrest after an uncommon suicide attempt by ingesting 3 g of chloroquine. After 66 min of cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary resuscitation (ECPR) was initiated, allowing cardiac function to recover. CONCLUSIONS: Chloroquine intoxication is a rare but serious condition due to its cardiac toxicity. Use of ECPR in this case of transient toxicity allowed a favorable evolution with little neurological impairment. BioMed Central 2021-03-15 /pmc/articles/PMC7958095/ /pubmed/33722251 http://dx.doi.org/10.1186/s13049-021-00850-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Ferry, Thomas
Amiet, Vivianne
Natterer, Julia
Perez, Marie-Hélène
Pfister, Raymond
Colombier, Sébastien
Longchamp, David
Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title_full Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title_fullStr Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title_full_unstemmed Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title_short Extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
title_sort extracorporeal cardiopulmonary resuscitation for severe chloroquine intoxication in a child – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958095/
https://www.ncbi.nlm.nih.gov/pubmed/33722251
http://dx.doi.org/10.1186/s13049-021-00850-0
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