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Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells

SIMPLE SUMMARY: Expression of the tyrosine kinase receptor ERBB2 in cancer cells leads to drug resistance. Autophagy, a “self-eating” process inside the cell, is a mechanism for drug resistance in cancer cells. It has been shown that ERBB2 activation leads to increased autophagy in breast cancer cel...

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Detalles Bibliográficos
Autores principales:	Chen, Yongqiang, Wang, Ruobing, Huang, Shujun, Henson, Elizabeth S., Bi, Jayce, Gibson, Spencer B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958130/ https://www.ncbi.nlm.nih.gov/pubmed/33801244 http://dx.doi.org/10.3390/cancers13051038

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