Cargando…
TAp73 represses NF-κB–mediated recruitment of tumor-associated macrophages in breast cancer
Infiltration of tumor-promoting immune cells is a strong driver of tumor progression. Especially the accumulation of macrophages in the tumor microenvironment is known to facilitate tumor growth and to correlate with poor prognosis in many tumor types. TAp73, a member of the p53/p63/p73 family, acts...
Autores principales: | Wolfsberger, Johanna, Sakil, Habib A. M., Zhou, Leilei, van Bree, Niek, Baldisseri, Elena, de Souza Ferreira, Sabrina, Zubillaga, Veronica, Stantic, Marina, Fritz, Nicolas, Hartman, Johan, Rolny, Charlotte, Wilhelm, Margareta T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958209/ https://www.ncbi.nlm.nih.gov/pubmed/33649219 http://dx.doi.org/10.1073/pnas.2017089118 |
Ejemplares similares
-
ΔNp73 enhances HIF-1α protein stability through repression of the ECV complex
por: Stantic, Marina, et al.
Publicado: (2018) -
ΔNp73 regulates the expression of the multidrug-resistance genes ABCB1 and ABCB5 in breast cancer and melanoma cells - a short report
por: Sakil, Habib A. M., et al.
Publicado: (2017) -
TAp73 transcriptionally represses BNIP3 expression
por: Petrova, Varvara, et al.
Publicado: (2015) -
JNK–NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress
por: Kostecka, A, et al.
Publicado: (2014) -
TAp73 promotes anabolism
por: Amelio, Ivano, et al.
Publicado: (2014)