Cargando…

SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study

INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chew, Kimberly Ann, Xu, Xin, Siongco, Paula, Villaraza, Steven, Phua, April Ka Sin, Wong, Zi Xuen, Chung, Chooi Yu, Tang, Ning, Chew, Effie, Henry, Christiani Jeyakumar, Koo, Edward, Chen, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958306/
https://www.ncbi.nlm.nih.gov/pubmed/33748399
http://dx.doi.org/10.1002/trc2.12141
_version_ 1783664801203879936
author Chew, Kimberly Ann
Xu, Xin
Siongco, Paula
Villaraza, Steven
Phua, April Ka Sin
Wong, Zi Xuen
Chung, Chooi Yu
Tang, Ning
Chew, Effie
Henry, Christiani Jeyakumar
Koo, Edward
Chen, Christopher
author_facet Chew, Kimberly Ann
Xu, Xin
Siongco, Paula
Villaraza, Steven
Phua, April Ka Sin
Wong, Zi Xuen
Chung, Chooi Yu
Tang, Ning
Chew, Effie
Henry, Christiani Jeyakumar
Koo, Edward
Chen, Christopher
author_sort Chew, Kimberly Ann
collection PubMed
description INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. RESULTS: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (P(upper body) = .04, P (lower body) = .06, P (core) = .05). More participants in the SINGER group attained good blood pressure control at month‐6 compared to FINGER (41% vs 19%; P = .06). DISCUSSION: This study is the first to compare the feasibility of multi‐domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi‐domain lifestyle interventions in preventing cognitive decline.
format Online
Article
Text
id pubmed-7958306
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-79583062021-03-19 SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study Chew, Kimberly Ann Xu, Xin Siongco, Paula Villaraza, Steven Phua, April Ka Sin Wong, Zi Xuen Chung, Chooi Yu Tang, Ning Chew, Effie Henry, Christiani Jeyakumar Koo, Edward Chen, Christopher Alzheimers Dement (N Y) Research Articles INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. RESULTS: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (P(upper body) = .04, P (lower body) = .06, P (core) = .05). More participants in the SINGER group attained good blood pressure control at month‐6 compared to FINGER (41% vs 19%; P = .06). DISCUSSION: This study is the first to compare the feasibility of multi‐domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi‐domain lifestyle interventions in preventing cognitive decline. John Wiley and Sons Inc. 2021-03-15 /pmc/articles/PMC7958306/ /pubmed/33748399 http://dx.doi.org/10.1002/trc2.12141 Text en © 2020 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Chew, Kimberly Ann
Xu, Xin
Siongco, Paula
Villaraza, Steven
Phua, April Ka Sin
Wong, Zi Xuen
Chung, Chooi Yu
Tang, Ning
Chew, Effie
Henry, Christiani Jeyakumar
Koo, Edward
Chen, Christopher
SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title_full SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title_fullStr SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title_full_unstemmed SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title_short SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
title_sort singapore geriatric intervention study to reduce physical frailty and cognitive decline (singer)–pilot: a feasibility study
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958306/
https://www.ncbi.nlm.nih.gov/pubmed/33748399
http://dx.doi.org/10.1002/trc2.12141
work_keys_str_mv AT chewkimberlyann singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT xuxin singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT siongcopaula singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT villarazasteven singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT phuaaprilkasin singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT wongzixuen singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT chungchooiyu singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT tangning singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT cheweffie singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT henrychristianijeyakumar singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT kooedward singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy
AT chenchristopher singaporegeriatricinterventionstudytoreducephysicalfrailtyandcognitivedeclinesingerpilotafeasibilitystudy