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SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study
INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958306/ https://www.ncbi.nlm.nih.gov/pubmed/33748399 http://dx.doi.org/10.1002/trc2.12141 |
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author | Chew, Kimberly Ann Xu, Xin Siongco, Paula Villaraza, Steven Phua, April Ka Sin Wong, Zi Xuen Chung, Chooi Yu Tang, Ning Chew, Effie Henry, Christiani Jeyakumar Koo, Edward Chen, Christopher |
author_facet | Chew, Kimberly Ann Xu, Xin Siongco, Paula Villaraza, Steven Phua, April Ka Sin Wong, Zi Xuen Chung, Chooi Yu Tang, Ning Chew, Effie Henry, Christiani Jeyakumar Koo, Edward Chen, Christopher |
author_sort | Chew, Kimberly Ann |
collection | PubMed |
description | INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. RESULTS: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (P(upper body) = .04, P (lower body) = .06, P (core) = .05). More participants in the SINGER group attained good blood pressure control at month‐6 compared to FINGER (41% vs 19%; P = .06). DISCUSSION: This study is the first to compare the feasibility of multi‐domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi‐domain lifestyle interventions in preventing cognitive decline. |
format | Online Article Text |
id | pubmed-7958306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79583062021-03-19 SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study Chew, Kimberly Ann Xu, Xin Siongco, Paula Villaraza, Steven Phua, April Ka Sin Wong, Zi Xuen Chung, Chooi Yu Tang, Ning Chew, Effie Henry, Christiani Jeyakumar Koo, Edward Chen, Christopher Alzheimers Dement (N Y) Research Articles INTRODUCTION: The SINGER pilot randomized controlled trial aims to examine the feasibility and acceptability of the Finnish Geriatric Intervention Study (FINGER) multi‐domain lifestyle interventions compared to Singaporean adaptations. METHODS: Seventy elderly participants were recruited and randomized into FINGER (n = 36) or SINGER (n = 34) interventions; involving physical exercise, cognitive training, diet, and vascular risk factors management, for 6 months. RESULTS: Both intervention groups were equally feasible and acceptable with participants completing at least 80% of the interventions. Body strength improved in both groups (P(upper body) = .04, P (lower body) = .06, P (core) = .05). More participants in the SINGER group attained good blood pressure control at month‐6 compared to FINGER (41% vs 19%; P = .06). DISCUSSION: This study is the first to compare the feasibility of multi‐domain interventions adapted to local culture with the FINGER interventions. The findings will be utilized for a larger study to provide evidence for the efficacy of multi‐domain lifestyle interventions in preventing cognitive decline. John Wiley and Sons Inc. 2021-03-15 /pmc/articles/PMC7958306/ /pubmed/33748399 http://dx.doi.org/10.1002/trc2.12141 Text en © 2020 The Authors. Alzheimer's & Dementia: Translational Research & Clinical Interventions published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Articles Chew, Kimberly Ann Xu, Xin Siongco, Paula Villaraza, Steven Phua, April Ka Sin Wong, Zi Xuen Chung, Chooi Yu Tang, Ning Chew, Effie Henry, Christiani Jeyakumar Koo, Edward Chen, Christopher SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title | SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title_full | SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title_fullStr | SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title_full_unstemmed | SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title_short | SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study |
title_sort | singapore geriatric intervention study to reduce physical frailty and cognitive decline (singer)–pilot: a feasibility study |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958306/ https://www.ncbi.nlm.nih.gov/pubmed/33748399 http://dx.doi.org/10.1002/trc2.12141 |
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