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Protective low-avidity anti-tumour CD8+ T cells are selectively attenuated by regulatory T cells

OBJECTIVES: Regulatory T cells (Treg) play a major role in the suppression of protective anti-tumour T cell responses. In the CT26 BALB/c murine model of colorectal carcinoma, Tregs differentially suppress responses to two characterised CD8+ T epitopes, AH1 and GSW11, which results in an absence of...

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Detalles Bibliográficos
Autores principales:	Sugiyarto, Gessa, Prossor, David, Dadas, Osman, Arcia-Anaya, E David, Elliott, Tim, James, Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958313/ https://www.ncbi.nlm.nih.gov/pubmed/33748824 http://dx.doi.org/10.1093/immadv/ltaa001

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