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IDO1 scavenges reactive oxygen species in myeloid-derived suppressor cells to prevent graft-versus-host disease
Tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1) also has an immunological function to suppress T cell activation in inflammatory circumstances, including graft-versus-host disease (GVHD), a fatal complication after allogeneic bone marrow transplantation (allo-BMT). Although the m...
Autores principales: | Ju, Ji-Min, Nam, Giri, Lee, Young-Kwan, Jung, Minho, Chang, Hanna, Kim, Woojin, Shon, Woo Jeong, Lim, Ji Young, Kim, Joo Young, Chang, Jun, Min, Chang Ki, Lee, Dong-Sup, Choi, Kyungho, Shin, Dong-Mi, Choi, Eun Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958359/ https://www.ncbi.nlm.nih.gov/pubmed/33649207 http://dx.doi.org/10.1073/pnas.2011170118 |
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