Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Xia, Yaoyao, He, Fang, Zhu, Congrui, Ren, Wenkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958491/
https://www.ncbi.nlm.nih.gov/pubmed/33715629
http://dx.doi.org/10.1186/s40168-021-01024-x
Descripción
Sumario:Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40168-021-01024-x.

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