Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, Xia, Yaoyao, He, Fang, Zhu, Congrui, Ren, Wenkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958491/
https://www.ncbi.nlm.nih.gov/pubmed/33715629
http://dx.doi.org/10.1186/s40168-021-01024-x
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author Wu, Xiaoyan
Xia, Yaoyao
He, Fang
Zhu, Congrui
Ren, Wenkai
author_facet Wu, Xiaoyan
Xia, Yaoyao
He, Fang
Zhu, Congrui
Ren, Wenkai
author_sort Wu, Xiaoyan
collection PubMed
description Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40168-021-01024-x.
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spelling pubmed-79584912021-03-16 Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities Wu, Xiaoyan Xia, Yaoyao He, Fang Zhu, Congrui Ren, Wenkai Microbiome Review Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology. Notably, the most striking characteristics of intestinal fungi are their extraintestinal functions. Here, we provide a comprehensive review of the importance of gut fungi in the regulation of intestinal, pulmonary, hepatic, renal, pancreatic, and brain functions, and we present possible opportunities for the application of gut mycobiota to alleviate/treat human diseases. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s40168-021-01024-x. BioMed Central 2021-03-14 /pmc/articles/PMC7958491/ /pubmed/33715629 http://dx.doi.org/10.1186/s40168-021-01024-x Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Wu, Xiaoyan
Xia, Yaoyao
He, Fang
Zhu, Congrui
Ren, Wenkai
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title_full Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title_fullStr Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title_full_unstemmed Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title_short Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
title_sort intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958491/
https://www.ncbi.nlm.nih.gov/pubmed/33715629
http://dx.doi.org/10.1186/s40168-021-01024-x
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