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Discovery and engineering of colchicine alkaloid biosynthesis
Few complete pathways are established for the biosynthesis of medicinal compounds from plants. Accordingly, many plant-derived therapeutics are isolated directly from medicinal plants or plant cell culture.(1) A lead example is colchicine, an FDA-approved treatment for inflammatory disorders that is...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958869/ https://www.ncbi.nlm.nih.gov/pubmed/32699417 http://dx.doi.org/10.1038/s41586-020-2546-8 |