MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation

BACKGROUND: Sarcopenia is a common skeletal disease related to myogenic disorders and muscle atrophy. Current clinical management has limited effectiveness. We sought to investigate the role of miR-1290 in myoblast differentiation and muscle atrophy. METHODS: By transfecting miR-1290 into C2C12 cell...

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Detalles Bibliográficos
Autores principales: Che, Ji, Xu, Cuidi, Wu, Yuanyuan, Jia, Peiyu, Han, Qi, Ma, Yantao, Wang, Xiaolei, Zheng, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958887/
https://www.ncbi.nlm.nih.gov/pubmed/33722298
http://dx.doi.org/10.1186/s13395-021-00262-9

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