MicroRNA-146a inhibition promotes total neurite outgrowth and suppresses cell apoptosis, inflammation, and STAT1/MYC pathway in PC12 and cortical neuron cellular Alzheimer's disease models

This study aimed to explore the effect of microRNA (miR)-146a inhibition on regulating cell apoptosis, total neurite outgrowth, inflammation, and STAT1/MYC pathway in Alzheimer's disease (AD). PC12 and cortical neuron cellular AD models were constructed by Aβ1-42 insult. For the former model, n...

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Detalles Bibliográficos
Autores principales: Ma, Yinghui, Ye, Jiye, Zhao, Li, Pan, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959174/
https://www.ncbi.nlm.nih.gov/pubmed/33729395
http://dx.doi.org/10.1590/1414-431X20209665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959174/
https://www.ncbi.nlm.nih.gov/pubmed/33729395
http://dx.doi.org/10.1590/1414-431X20209665

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