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FTY720-derivatives do not induce FTY720-like lymphopenia

FTY720 is an immunosuppressive multiple sclerosis (MS) drug that stimulates the expression of neuroprotective brain-derived-neurotrophic-factor (BDNF). In vivo preclinical data suggest that FTY720 could be beneficial for treating Parkinson’s patients, though its immunosuppressive effects might limit...

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Detalles Bibliográficos
Autores principales: Segura-Ulate, Ismael, Belcher, Troy K., Vidal-Martinez, Guadalupe, Vargas-Medrano, Javier, Perez, Ruth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959251/
https://www.ncbi.nlm.nih.gov/pubmed/28363412
http://dx.doi.org/10.1016/j.jphs.2017.02.006