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Application of xCELLigence real-time cell analysis to the microplate assay for pertussis toxin induced clustering in CHO cells

The microplate assay with Chinese Hamster Ovary (CHO) cells is currently used as a safety test to monitor the residual pertussis toxin (PT) amount in acellular pertussis antigens prior to vaccine formulation. The assay is based on the findings that the exposure of CHO cells to PT results in a concen...

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Detalles Bibliográficos
Autores principales:	Bernardo, Lidice, Corallo, Lucas, Caterini, Judy, Su, Jin, Gisonni-Lex, Lucy, Gajewska, Beata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959359/ https://www.ncbi.nlm.nih.gov/pubmed/33720984 http://dx.doi.org/10.1371/journal.pone.0248491

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