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Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume

BACKGROUND: Ischemic stroke is a common and debilitating disease with limited treatment options. Protease activated receptor 1 (PAR1) is a fundamental cell signaling mediator in the central nervous system (CNS). It can be activated by many proteases including thrombin and plasmin, with various down-...

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Detalles Bibliográficos
Autores principales:	Shavit-Stein, Efrat, Mindel, Ekaterina, Gofrit, Shany Guly, Chapman, Joab, Maggio, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959388/ https://www.ncbi.nlm.nih.gov/pubmed/33720950 http://dx.doi.org/10.1371/journal.pone.0248431

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