Cargando…

EphB6 Regulates TFEB-Lysosomal Pathway and Survival of Disseminated Indolent Breast Cancer Cells

SIMPLE SUMMARY: A large number of estrogen receptor-positive breast cancer patients show relapses at the metastatic site up to 20 years after the removal of the primary tumor. This phenomenon, called “metastatic dormancy”, is a particularly dangerous aspect of cancers, as it affects patients conside...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zangrossi, Manuela, Romani, Patrizia, Chakravarty, Probir, Ratcliffe, Colin D.H., Hooper, Steven, Dori, Martina, Forcato, Mattia, Bicciato, Silvio, Dupont, Sirio, Sahai, Erik, Montagner, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959459/ https://www.ncbi.nlm.nih.gov/pubmed/33802447 http://dx.doi.org/10.3390/cancers13051079

Ejemplares similares

A Lung Organotypic Coculture Reveals a Role for TFEB-Lysosomal Axis in the Survival of Disseminated Dormant Cancer Cells
por: Zangrossi, Manuela, et al.
Publicado: (2021)

Low Expression of EphB2, EphB3, and EphB4 in Bladder Cancer: Novel Potential Indicators of Muscular Invasion
por: Lee, Tae Ho, et al.
Publicado: (2021)

Reelin induces EphB activation
por: Bouché, Elisabeth, et al.
Publicado: (2013)

The Roles of EphB2 in Cancer
por: Liu, Wei, et al.
Publicado: (2022)

Structure of the EphB6 receptor ectodomain
por: Mason, Emilia O., et al.
Publicado: (2021)

The Differential Expression of EphB2 and EphB4 Receptor Kinases in Normal Bladder and in Transitional Cell Carcinoma of the Bladder
por: Li, Xiuqing, et al.
Publicado: (2014)

EphB4 as a therapeutic target in mesothelioma
por: Liu, Ren, et al.
Publicado: (2013)

Neuropsin cleaves EphB2 in the amygdala to control anxiety
por: Attwood, Benjamin, et al.
Publicado: (2011)

EphB2: potential therapeutic target for Alzheimer’s disease
Publicado: (2011)

Preferential Control of Basal Dendritic Protrusions by EphB2
por: Kayser, Matthew S., et al.
Publicado: (2011)

EphB/ephrinB Signaling in Cell Adhesion and Migration
por: Park, Inji, et al.
Publicado: (2015)

Paradoxes of the EphB1 receptor in malignant brain tumors
por: Wei, Wenqiang, et al.
Publicado: (2017)

EphB4/EphrinB2 therapeutics in Rhabdomyosarcoma
por: Randolph, Matthew E., et al.
Publicado: (2017)

Key role for EphB2 receptor in kidney fibrosis
por: Huang, Zhimin, et al.
Publicado: (2021)

Differential Roles for EphA and EphB Signaling in Segregation and Patterning of Central Vestibulocochlear Nerve Projections
por: Allen-Sharpley, Michelle R., et al.
Publicado: (2013)

Evaluation of EphA2 and EphB4 as Targets for Image-Guided Colorectal Cancer Surgery
por: Stammes, Marieke A., et al.
Publicado: (2017)

Inhibition of choroidal neovascularization by anti-EphB4 monoclonal antibody
por: SU, DONGFENG, et al.
Publicado: (2013)

EphB4 forward signalling regulates lymphatic valve development
por: Zhang, Gu, et al.
Publicado: (2015)

EphB4 mediates resistance to antiangiogenic therapy in experimental glioma
por: Uhl, Christian, et al.
Publicado: (2018)

EphB2 mediates social isolation-induced memory forgetting
por: Wu, Xin-Rong, et al.
Publicado: (2020)

The EphB6 Receptor: Kinase-Dead but Very Much Alive
por: Strozen, Timothy G., et al.
Publicado: (2021)

EphrinB2–EphB4 Signaling in Neurooncological Disease
por: Piffko, Andras, et al.
Publicado: (2022)

Cross-talk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination
por: Montagner, Marco, et al.
Publicado: (2020)

Molecular Determinants of EphA2 and EphB2 Antagonism Enable the Design of Ligands with Improved Selectivity
por: Guidetti, Lorenzo, et al.
Publicado: (2023)

TFEB‐dependent lysosome biogenesis is required for senescence
por: Curnock, Rachel, et al.
Publicado: (2023)

Investigation of the expression of the EphB4 receptor tyrosine kinase in prostate carcinoma
por: Lee, Yen-Ching, et al.
Publicado: (2005)

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus
por: Henkemeyer, Mark, et al.
Publicado: (2003)

Involvement of EphB1 Receptors Signalling in Models of Inflammatory and Neuropathic Pain
por: Cibert-Goton, Vincent, et al.
Publicado: (2013)

The composition of EphB2 clusters determines the strength in the cellular repulsion response
por: Schaupp, Andreas, et al.
Publicado: (2014)

Critical roles for EphB and ephrin-B bidirectional signaling in retinocollicular mapping
por: Thakar, Sonal, et al.
Publicado: (2011)

EphB6 overexpression and Apc mutation together promote colorectal cancer
por: Xu, Dan, et al.
Publicado: (2016)

EphB3 signaling propagates synaptic dysfunction in the traumatic injured brain
por: Perez, Enmanuel J., et al.
Publicado: (2016)

Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer
por: de Muijnck, Cansu, et al.
Publicado: (2020)

Prognostic and Clinicopathological Significance of EphB3 and Dysadherin Expression in Extrahepatic Cholangiocarcinoma
por: Wu, Zhengchun, et al.
Publicado: (2020)

The ephrin receptor EphB2 regulates the connectivity and activity of enteric neurons
por: Bodin, Raphael, et al.
Publicado: (2021)

Scaffold Protein Lnx1 Stabilizes EphB Receptor Kinases for Synaptogenesis
por: Li, Na, et al.
Publicado: (2022)

Neddylation of EphB1 Regulates Its Activity and Associates with Liver Fibrosis
por: Li, Rongxin, et al.
Publicado: (2023)

Colorectal cancer-associated mutations impair EphB1 kinase function
por: Kim, Yunyoung, et al.
Publicado: (2023)

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
por: Liang, Lung-Yu, et al.
Publicado: (2021)

Docetaxel enhances lysosomal function through TFEB activation
por: Zhang, Jianbin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ruki9kdkpoalraf52s3vccqlrl