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Macropinocytosis-mediated membrane recycling drives neural crest migration by delivering F-actin to the lamellipodium

Individual cell migration requires front-to-back polarity manifested by lamellipodial extension. At present, it remains debated whether and how membrane motility mediates this cell morphological change. To gain insights into these processes, we perform live imaging and molecular perturbation of migr...

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Detalles Bibliográficos
Autores principales: Li, Yuwei, Gonzalez, Walter G., Andreev, Andrey, Tang, Weiyi, Gandhi, Shashank, Cunha, Alexandre, Prober, David, Lois, Carlos, Bronner, Marianne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959501/
https://www.ncbi.nlm.nih.gov/pubmed/33087579
http://dx.doi.org/10.1073/pnas.2007229117