Collective cancer cell invasion requires RNA accumulation at the invasive front

Localization of RNAs at protrusive regions of cells is important for single-cell migration on two-dimensional surfaces. Protrusion-enriched RNAs encode factors linked to cancer progression, such as the RAB13 GTPase and the NET1 guanine nucleotide exchange factor, and are regulated by the tumor-suppr...

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Detalles Bibliográficos
Autores principales: Chrisafis, George, Wang, Tianhong, Moissoglu, Konstadinos, Gasparski, Alexander N., Ng, Yeap, Weigert, Roberto, Lockett, Stephen J., Mili, Stavroula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959543/
https://www.ncbi.nlm.nih.gov/pubmed/33060293
http://dx.doi.org/10.1073/pnas.2010872117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959543/
https://www.ncbi.nlm.nih.gov/pubmed/33060293
http://dx.doi.org/10.1073/pnas.2010872117

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