Bifidobacterium alters the gut microbiota and modulates the functional metabolism of T regulatory cells in the context of immune checkpoint blockade

Immune checkpoint-blocking antibodies that attenuate immune tolerance have been used to effectively treat cancer, but they can also trigger severe immune-related adverse events. Previously, we found that Bifidobacterium could mitigate intestinal immunopathology in the context of CTLA-4 blockade in m...

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Detalles Bibliográficos
Autores principales: Sun, Shan, Luo, Lingjie, Liang, Wenhua, Yin, Qian, Guo, Jing, Rush, Anthony M., Lv, Zhibao, Liang, Qiming, Fischbach, Michael A., Sonnenburg, Justin L., Dodd, Dylan, Davis, Mark M., Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959554/
https://www.ncbi.nlm.nih.gov/pubmed/33077598
http://dx.doi.org/10.1073/pnas.1921223117

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