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Structural basis of Chikungunya virus inhibition by monoclonal antibodies

Chikungunya virus (CHIKV) is an emerging viral pathogen that causes both acute and chronic debilitating arthritis. Here, we describe the functional and structural basis as to how two anti-CHIKV monoclonal antibodies, CHK-124 and CHK-263, potently inhibit CHIKV infection in vitro and in vivo. Our in...

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Detalles Bibliográficos
Autores principales:	Zhou, Qun Fei, Fox, Julie M., Earnest, James T., Ng, Thiam-Seng, Kim, Arthur S., Fibriansah, Guntur, Kostyuchenko, Victor A., Shi, Jian, Shu, Bo, Diamond, Michael S., Lok, Shee-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959576/ https://www.ncbi.nlm.nih.gov/pubmed/33087569 http://dx.doi.org/10.1073/pnas.2008051117

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