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Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm

BACKGROUND: Otitis media (OM) is the infection and inflammation of the mucous membrane covering the Eustachian with the airy cavities of the middle ear and temporal bone. OM is also one of the most common ailments. In clinical practice, the diagnosis of OM is carried out by visual inspection of otos...

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Autores principales: Alhudhaif, Adi, Cömert, Zafer, Polat, Kemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959604/
https://www.ncbi.nlm.nih.gov/pubmed/33817048
http://dx.doi.org/10.7717/peerj-cs.405
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author Alhudhaif, Adi
Cömert, Zafer
Polat, Kemal
author_facet Alhudhaif, Adi
Cömert, Zafer
Polat, Kemal
author_sort Alhudhaif, Adi
collection PubMed
description BACKGROUND: Otitis media (OM) is the infection and inflammation of the mucous membrane covering the Eustachian with the airy cavities of the middle ear and temporal bone. OM is also one of the most common ailments. In clinical practice, the diagnosis of OM is carried out by visual inspection of otoscope images. This vulnerable process is subjective and error-prone. METHODS: In this study, a novel computer-aided decision support model based on the convolutional neural network (CNN) has been developed. To improve the generalized ability of the proposed model, a combination of the channel and spatial model (CBAM), residual blocks, and hypercolumn technique is embedded into the proposed model. All experiments were performed on an open-access tympanic membrane dataset that consists of 956 otoscopes images collected into five classes. RESULTS: The proposed model yielded satisfactory classification achievement. The model ensured an overall accuracy of 98.26%, sensitivity of 97.68%, and specificity of 99.30%. The proposed model produced rather superior results compared to the pre-trained CNNs such as AlexNet, VGG-Nets, GoogLeNet, and ResNets. Consequently, this study points out that the CNN model equipped with the advanced image processing techniques is useful for OM diagnosis. The proposed model may help to field specialists in achieving objective and repeatable results, decreasing misdiagnosis rate, and supporting the decision-making processes.
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spelling pubmed-79596042021-04-02 Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm Alhudhaif, Adi Cömert, Zafer Polat, Kemal PeerJ Comput Sci Bioinformatics BACKGROUND: Otitis media (OM) is the infection and inflammation of the mucous membrane covering the Eustachian with the airy cavities of the middle ear and temporal bone. OM is also one of the most common ailments. In clinical practice, the diagnosis of OM is carried out by visual inspection of otoscope images. This vulnerable process is subjective and error-prone. METHODS: In this study, a novel computer-aided decision support model based on the convolutional neural network (CNN) has been developed. To improve the generalized ability of the proposed model, a combination of the channel and spatial model (CBAM), residual blocks, and hypercolumn technique is embedded into the proposed model. All experiments were performed on an open-access tympanic membrane dataset that consists of 956 otoscopes images collected into five classes. RESULTS: The proposed model yielded satisfactory classification achievement. The model ensured an overall accuracy of 98.26%, sensitivity of 97.68%, and specificity of 99.30%. The proposed model produced rather superior results compared to the pre-trained CNNs such as AlexNet, VGG-Nets, GoogLeNet, and ResNets. Consequently, this study points out that the CNN model equipped with the advanced image processing techniques is useful for OM diagnosis. The proposed model may help to field specialists in achieving objective and repeatable results, decreasing misdiagnosis rate, and supporting the decision-making processes. PeerJ Inc. 2021-02-23 /pmc/articles/PMC7959604/ /pubmed/33817048 http://dx.doi.org/10.7717/peerj-cs.405 Text en © 2021 Alhudhaif et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Computer Science) and either DOI or URL of the article must be cited.
spellingShingle Bioinformatics
Alhudhaif, Adi
Cömert, Zafer
Polat, Kemal
Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title_full Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title_fullStr Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title_full_unstemmed Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title_short Otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
title_sort otitis media detection using tympanic membrane images with a novel multi-class machine learning algorithm
topic Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959604/
https://www.ncbi.nlm.nih.gov/pubmed/33817048
http://dx.doi.org/10.7717/peerj-cs.405
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