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Comparative Assessment of the Activity of Racemic and Dextrorotatory Forms of Thioctic (Alpha-Lipoic) Acid in Low Back Pain: Preclinical Results and Clinical Evidences From an Open Randomized Trial
Peripheral neuropathies, characterized by altered nociceptive and muscular functions, are related to oxidative stress. Thioctic acid is a natural antioxidant existing as two optical isomers, but most clinically used as racemic mixture. The present study investigated the central nervous system’s chan...
Autores principales: | Pacini, Alessandra, Tomassoni, Daniele, Trallori, Elena, Micheli, Laura, Amenta, Francesco, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Traini, Enea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959756/ https://www.ncbi.nlm.nih.gov/pubmed/33732153 http://dx.doi.org/10.3389/fphar.2021.607572 |
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