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A fractional-order compartmental model for the spread of the COVID-19 pandemic
We propose a time-fractional compartmental model (SEI [Formula: see text] I [Formula: see text] HRD) comprising of the susceptible, exposed, infected (asymptomatic and symptomatic), hospitalized, recovered and dead population for the COVID-19 pandemic. We study the properties and dynamics of the pro...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959886/ https://www.ncbi.nlm.nih.gov/pubmed/33746459 http://dx.doi.org/10.1016/j.cnsns.2021.105764 |
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author | Biala, T.A. Khaliq, A.Q.M. |
author_facet | Biala, T.A. Khaliq, A.Q.M. |
author_sort | Biala, T.A. |
collection | PubMed |
description | We propose a time-fractional compartmental model (SEI [Formula: see text] I [Formula: see text] HRD) comprising of the susceptible, exposed, infected (asymptomatic and symptomatic), hospitalized, recovered and dead population for the COVID-19 pandemic. We study the properties and dynamics of the proposed model. The conditions under which the disease-free and endemic equilibrium points are asymptotically stable are discussed. Furthermore, we study the sensitivity of the parameters and use the data from Tennessee state (as a case study) to discuss identifiability of the parameters of the model. The non-negative parameters in the model are obtained by solving inverse problems with empirical data from California, Florida, Georgia, Maryland, Tennessee, Texas, Washington and Wisconsin. The basic reproduction number is seen to be slightly above the critical value of one suggesting that stricter measures such as the use of face-masks, social distancing, contact tracing, and even longer stay-at-home orders need to be enforced in order to mitigate the spread of the virus. As stay-at-home orders are rescinded in some of these states, we see that the number of cases began to increase almost immediately and may continue to rise until the end of the year 2020 unless stricter measures are taken. |
format | Online Article Text |
id | pubmed-7959886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79598862021-03-16 A fractional-order compartmental model for the spread of the COVID-19 pandemic Biala, T.A. Khaliq, A.Q.M. Commun Nonlinear Sci Numer Simul Research Paper We propose a time-fractional compartmental model (SEI [Formula: see text] I [Formula: see text] HRD) comprising of the susceptible, exposed, infected (asymptomatic and symptomatic), hospitalized, recovered and dead population for the COVID-19 pandemic. We study the properties and dynamics of the proposed model. The conditions under which the disease-free and endemic equilibrium points are asymptotically stable are discussed. Furthermore, we study the sensitivity of the parameters and use the data from Tennessee state (as a case study) to discuss identifiability of the parameters of the model. The non-negative parameters in the model are obtained by solving inverse problems with empirical data from California, Florida, Georgia, Maryland, Tennessee, Texas, Washington and Wisconsin. The basic reproduction number is seen to be slightly above the critical value of one suggesting that stricter measures such as the use of face-masks, social distancing, contact tracing, and even longer stay-at-home orders need to be enforced in order to mitigate the spread of the virus. As stay-at-home orders are rescinded in some of these states, we see that the number of cases began to increase almost immediately and may continue to rise until the end of the year 2020 unless stricter measures are taken. Elsevier B.V. 2021-07 2021-02-19 /pmc/articles/PMC7959886/ /pubmed/33746459 http://dx.doi.org/10.1016/j.cnsns.2021.105764 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Research Paper Biala, T.A. Khaliq, A.Q.M. A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title | A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title_full | A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title_fullStr | A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title_full_unstemmed | A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title_short | A fractional-order compartmental model for the spread of the COVID-19 pandemic |
title_sort | fractional-order compartmental model for the spread of the covid-19 pandemic |
topic | Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959886/ https://www.ncbi.nlm.nih.gov/pubmed/33746459 http://dx.doi.org/10.1016/j.cnsns.2021.105764 |
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