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Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project

AIMS: Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents based on ECG data from the CARDIOPED project, a large-scale ge...

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Autores principales: Cismaru, Gabriel, Lazea, Cecilia, Mureşan, Lucian, Gusetu, Gabriel, Rosu, Radu, Pop, Dana, Zdrenghea, Dumitru, Farcaş, Anca Daniela, Căinap, Simona Sorana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959889/
https://www.ncbi.nlm.nih.gov/pubmed/33747254
http://dx.doi.org/10.1155/2021/6657982
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author Cismaru, Gabriel
Lazea, Cecilia
Mureşan, Lucian
Gusetu, Gabriel
Rosu, Radu
Pop, Dana
Zdrenghea, Dumitru
Farcaş, Anca Daniela
Căinap, Simona Sorana
author_facet Cismaru, Gabriel
Lazea, Cecilia
Mureşan, Lucian
Gusetu, Gabriel
Rosu, Radu
Pop, Dana
Zdrenghea, Dumitru
Farcaş, Anca Daniela
Căinap, Simona Sorana
author_sort Cismaru, Gabriel
collection PubMed
description AIMS: Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents based on ECG data from the CARDIOPED project, a large-scale general population of children who participated in a screening program in Transylvania, Romania. METHODS AND RESULTS: A total of 22,411 ECGs of participants aged 6 to 18 years old from a school-based ECG screening were obtained between February 2015 and December 2015 in Transylvania, Romania. Three pediatric cardiologists manually reviewed each ECG. P-wave duration, voltage, axis, and correlation with gender and age were analyzed. The mean P-wave duration was 88 ± 10.7 ms, with a maximum duration of 128 ms. P-wave showed a positive correlation with age but did not differ between sexes. There was a positive correlation between the P-wave duration and the heart rate, but not with the body max index. The mean P-wave axis was 40.4 ± 31.1, and the mean P-wave amplitude was 0.12 ± 0.03 mV. CONCLUSION: In this study on many pediatric subjects, we have provided normal limits for the P-wave in Romanian children aged 6-18 years. Our findings are useful for creating interpretation guidelines for pediatric ECG.
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spelling pubmed-79598892021-03-19 Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project Cismaru, Gabriel Lazea, Cecilia Mureşan, Lucian Gusetu, Gabriel Rosu, Radu Pop, Dana Zdrenghea, Dumitru Farcaş, Anca Daniela Căinap, Simona Sorana Dis Markers Research Article AIMS: Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents based on ECG data from the CARDIOPED project, a large-scale general population of children who participated in a screening program in Transylvania, Romania. METHODS AND RESULTS: A total of 22,411 ECGs of participants aged 6 to 18 years old from a school-based ECG screening were obtained between February 2015 and December 2015 in Transylvania, Romania. Three pediatric cardiologists manually reviewed each ECG. P-wave duration, voltage, axis, and correlation with gender and age were analyzed. The mean P-wave duration was 88 ± 10.7 ms, with a maximum duration of 128 ms. P-wave showed a positive correlation with age but did not differ between sexes. There was a positive correlation between the P-wave duration and the heart rate, but not with the body max index. The mean P-wave axis was 40.4 ± 31.1, and the mean P-wave amplitude was 0.12 ± 0.03 mV. CONCLUSION: In this study on many pediatric subjects, we have provided normal limits for the P-wave in Romanian children aged 6-18 years. Our findings are useful for creating interpretation guidelines for pediatric ECG. Hindawi 2021-03-06 /pmc/articles/PMC7959889/ /pubmed/33747254 http://dx.doi.org/10.1155/2021/6657982 Text en Copyright © 2021 Gabriel Cismaru et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Cismaru, Gabriel
Lazea, Cecilia
Mureşan, Lucian
Gusetu, Gabriel
Rosu, Radu
Pop, Dana
Zdrenghea, Dumitru
Farcaş, Anca Daniela
Căinap, Simona Sorana
Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title_full Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title_fullStr Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title_full_unstemmed Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title_short Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
title_sort validation of normal p-wave parameters in a large unselected pediatric population of north-western romania: results of the cardioped project
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7959889/
https://www.ncbi.nlm.nih.gov/pubmed/33747254
http://dx.doi.org/10.1155/2021/6657982
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