Kupffer Cells Mediate Systemic Antifungal Immunity

Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance...

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Detalles Bibliográficos
Autores principales: Coelho, Carolina, Drummond, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2019
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960509/
https://www.ncbi.nlm.nih.gov/pubmed/31735512
http://dx.doi.org/10.1016/j.it.2019.11.001
Descripción
Sumario:Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance of understanding tissue-specific immune responses in disease pathogenesis.

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