Kupffer Cells Mediate Systemic Antifungal Immunity

Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance...

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Detalles Bibliográficos
Autores principales: Coelho, Carolina, Drummond, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2019
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960509/
https://www.ncbi.nlm.nih.gov/pubmed/31735512
http://dx.doi.org/10.1016/j.it.2019.11.001
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author Coelho, Carolina
Drummond, Rebecca A.
author_facet Coelho, Carolina
Drummond, Rebecca A.
author_sort Coelho, Carolina
collection PubMed
description Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance of understanding tissue-specific immune responses in disease pathogenesis.
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spelling pubmed-79605092021-03-19 Kupffer Cells Mediate Systemic Antifungal Immunity Coelho, Carolina Drummond, Rebecca A. Trends Immunol Spotlight Patients with liver dysfunction have increased susceptibility to fungal infections. A recently published article (Sun et al.) describes the potential mechanism underlying this association, which maps to the antifungal activity of liver-resident Kupffer cells. This research highlights the importance of understanding tissue-specific immune responses in disease pathogenesis. Elsevier Science Ltd 2019-12 /pmc/articles/PMC7960509/ /pubmed/31735512 http://dx.doi.org/10.1016/j.it.2019.11.001 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Spotlight
Coelho, Carolina
Drummond, Rebecca A.
Kupffer Cells Mediate Systemic Antifungal Immunity
title Kupffer Cells Mediate Systemic Antifungal Immunity
title_full Kupffer Cells Mediate Systemic Antifungal Immunity
title_fullStr Kupffer Cells Mediate Systemic Antifungal Immunity
title_full_unstemmed Kupffer Cells Mediate Systemic Antifungal Immunity
title_short Kupffer Cells Mediate Systemic Antifungal Immunity
title_sort kupffer cells mediate systemic antifungal immunity
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960509/
https://www.ncbi.nlm.nih.gov/pubmed/31735512
http://dx.doi.org/10.1016/j.it.2019.11.001
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