CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA

Proper expression of Homeobox A cluster genes (HoxA) is essential for embryonic stem cell (ESC) differentiation and individual development. However, mechanisms controlling precise spatiotemporal expression of HoxA during early ESC differentiation remain poorly understood. Herein, we identified a fun...

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Detalles Bibliográficos
Autores principales: Su, Guangsong, Wang, Wenbin, Chen, Jun, Liu, Man, Zheng, Jian, Guo, Dianhao, Bi, Jinfang, Zhao, Zhongfang, Shi, Jiandang, Zhang, Lei, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960549/
https://www.ncbi.nlm.nih.gov/pubmed/33581110
http://dx.doi.org/10.1016/j.jbc.2021.100413

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