Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells

The use of mouse derived mammary organoids can provide a unique strategy to study mammary gland development across a normal life cycle, as well as offering insights into how malignancies form and progress. Substantial cellular and epigenomic changes are triggered in response to pregnancy hormones, a...

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Detalles Bibliográficos
Autores principales: Ciccone, Michael F., Trousdell, Marygrace C., dos Santos, Camila O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960614/
https://www.ncbi.nlm.nih.gov/pubmed/33131024
http://dx.doi.org/10.1007/s10911-020-09465-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960614/
https://www.ncbi.nlm.nih.gov/pubmed/33131024
http://dx.doi.org/10.1007/s10911-020-09465-0

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