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Apelin Rejuvenates Aged Human Mesenchymal Stem Cells by Regulating Autophagy and Improves Cardiac Protection After Infarction

The protective effects of mesenchymal stem cell (MSC)-based therapy for myocardial infarction (MI) are largely hampered as they age. Apelin is an endogenous ligand of its receptor APJ and plays an essential role in regulating multiple biological activities including MSC proliferation and survival. I...

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Detalles Bibliográficos
Autores principales:	Zhang, Hao, Zhao, Chengling, Jiang, Guojun, Hu, Bei, Zheng, Huifeng, Hong, Yimei, Cui, Zhen, Shi, Linli, Li, Xin, Lin, Fang, Ding, Yue, Wei, Lu, Li, Mimi, Liang, Xiaoting, Zhang, Yuelin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960672/ https://www.ncbi.nlm.nih.gov/pubmed/33738284 http://dx.doi.org/10.3389/fcell.2021.628463

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