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Structural insights of human N-acetyltransferase 10 and identification of its potential novel inhibitors
N-acetyltransferase 10 (NAT10), is an acetyltransferase that regulates RNA stability and translation processes. Association of NAT10 with several diseases including cancer, makes it a promising therapeutic target. Remodelin is the only known NAT10 inhibitor, but the structural information related to...
Autores principales: | Dalhat, Mahmood Hassan, Altayb, Hisham N., Khan, Mohammad Imran, Choudhry, Hani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960695/ https://www.ncbi.nlm.nih.gov/pubmed/33723305 http://dx.doi.org/10.1038/s41598-021-84908-0 |
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