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Structural insights of human N-acetyltransferase 10 and identification of its potential novel inhibitors

N-acetyltransferase 10 (NAT10), is an acetyltransferase that regulates RNA stability and translation processes. Association of NAT10 with several diseases including cancer, makes it a promising therapeutic target. Remodelin is the only known NAT10 inhibitor, but the structural information related to...

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Detalles Bibliográficos
Autores principales: Dalhat, Mahmood Hassan, Altayb, Hisham N., Khan, Mohammad Imran, Choudhry, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960695/
https://www.ncbi.nlm.nih.gov/pubmed/33723305
http://dx.doi.org/10.1038/s41598-021-84908-0

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