Cargando…

Type 2 diabetes progression differently affects endothelial function and vascular contractility in the aorta and the pulmonary artery

Type 2 diabetes (T2D) is associated with cardiovascular and pulmonary disease. How T2D affects pulmonary endothelial function is not well characterized. We investigated the effects of T2D progression on contractility machinery and endothelial function in the pulmonary and systemic circulation and th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Melo, Bernardete F., Prieto-Lloret, Jesus, Cabral, Marlene D., Martins, Fatima O., Martins, Inês B., Sacramento, Joana F., Ruivo, Pedro, Carvalho, Tânia, Conde, Silvia V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960698/ https://www.ncbi.nlm.nih.gov/pubmed/33723367 http://dx.doi.org/10.1038/s41598-021-85606-7

Ejemplares similares

Chronic Intermittent Hypoxia Induces Early-Stage Metabolic Dysfunction Independently of Adipose Tissue Deregulation
por: Martins, Fátima O., et al.
Publicado: (2021)

Immunity and the carotid body: implications for metabolic diseases
por: Conde, Silvia V., et al.
Publicado: (2020)

Exploring the Mediators that Promote Carotid Body Dysfunction in Type 2 Diabetes and Obesity Related Syndromes
por: Sacramento, Joana F., et al.
Publicado: (2020)

Long-Term Hypercaloric Diet Consumption Exacerbates Age-Induced Dysmetabolism and Carotid Body Dysfunction: Beneficial Effects of CSN Denervation
por: Melo, Bernardete F., et al.
Publicado: (2022)

Peripheral Dopamine Directly Acts on Insulin-Sensitive Tissues to Regulate Insulin Signaling and Metabolic Function
por: Tavares, Gabriela, et al.
Publicado: (2021)

Bioelectronic modulation of carotid sinus nerve activity in the rat: a potential therapeutic approach for type 2 diabetes
por: Sacramento, Joana F., et al.
Publicado: (2018)

Blood Pressure Regulation by the Carotid Sinus Nerve: Clinical Implications for Carotid Body Neuromodulation
por: Conde, Silvia V., et al.
Publicado: (2022)

Evaluating the Impact of Different Hypercaloric Diets on Weight Gain, Insulin Resistance, Glucose Intolerance, and its Comorbidities in Rats
por: Melo, Bernardete F., et al.
Publicado: (2019)

Chronic Intermittent Hypoxia-Induced Dysmetabolism Is Associated with Hepatic Oxidative Stress, Mitochondrial Dysfunction and Inflammation
por: Fernandes, Joana L., et al.
Publicado: (2023)

The involvement of prostaglandins in the contractile function of the aorta by aldosterone
por: Eatman, Danita, et al.
Publicado: (2011)

Fenofibrate improves vascular endothelial function and contractility in diabetic mice
por: Xu, Nan, et al.
Publicado: (2018)

A(2) Adenosine Receptors Mediate Whole-Body Insulin Sensitivity in a Prediabetes Animal Model: Primary Effects on Skeletal Muscle
por: Sacramento, Joana F., et al.
Publicado: (2020)

Endothelial-Dependent and Independent Vascular Relaxation Effect of Tetrahydropalmatine on Rat Aorta
por: Zhou, Zhong-Yan, et al.
Publicado: (2019)

Increased Vascular Contractility in Hypertension Results From Impaired Endothelial Calcium Signaling
por: Wilson, Calum, et al.
Publicado: (2019)

Endothelial [Ca(2+)](i) is an integrating signal for the vascular tone in rat aortae
por: Huang, Tung-Yi, et al.
Publicado: (2001)

Role of ROCK upregulation in endothelial and smooth muscle vascular functions in diabetic rat aorta
por: Cicek, Figen Amber, et al.
Publicado: (2013)

Effects of Continuous and Accumulated Exercise on Endothelial Function in Rat Aorta
por: Martinez, Juliana Edwiges, et al.
Publicado: (2017)

Recognizing a “Hot Phase” of An Arrhythmogenic Left Ventricular Cardiomyopathy: A Case Report
por: Cabral, Margarida, et al.
Publicado: (2023)

Undercarboxylated osteocalcin has no adverse effect on endothelial function in rabbit aorta or human vascular cells
por: Tacey, Alexander, et al.
Publicado: (2020)

A Metabolic Signature to Monitor Endothelial Cell Differentiation, Activation, and Vascular Organization
por: Lopes-Coelho, Filipa, et al.
Publicado: (2022)

Coarctation of Aorta in Turner Mosaicism
por: Gorito, Vanessa, et al.
Publicado: (2021)

Elucidation of the profound antagonism of contractile action of phenylephrine in rat aorta effected by an atypical sympathomimetic decongestant
por: Rizvić, Eldina, et al.
Publicado: (2017)

BMPER Improves Vascular Remodeling and the Contractile Vascular SMC Phenotype
por: Pankratz, Franziska, et al.
Publicado: (2023)

Vascular Involvements Are Common in the Branch Arteries of the Abdominal Aorta Rather Than in the Aorta in Vascular Ehlers-Danlos Syndrome
por: Akutsu, Koichi, et al.
Publicado: (2022)

Anti-Platelet Therapy with Clopidogrel Prevents Endothelial Dysfunction and Vascular Remodeling in Aortas from Hypertensive Rats
por: Giachini, Fernanda R., et al.
Publicado: (2014)

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity
por: Lu, Chang-Wu, et al.
Publicado: (2017)

Vascular Endothelial Dysfunction in the Thoracic Aorta of Rats with Ischemic Acute Kidney Injury: Contribution of Indoxyl Sulfate
por: Nakagawa, Keisuke, et al.
Publicado: (2022)

Endothelial γ-Glutamyltransferase Contributes to the Vasorelaxant Effect of S-Nitrosoglutathione in Rat Aorta
por: Dahboul, Fatima, et al.
Publicado: (2012)

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility
por: Angulo-Urarte, Ana, et al.
Publicado: (2018)

Impact of Treatment Modality on Vascular Function in Coarctation of the Aorta: The LOVE‐COARCT Study
por: Martins, José D., et al.
Publicado: (2019)

Impact of Short-Term (+)-JQ1 Exposure on Mouse Aorta: Unanticipated Inhibition of Smooth Muscle Contractility
por: Yan, Binjie, et al.
Publicado: (2023)

Purines and Carotid Body: New Roles in Pathological Conditions
por: Conde, Silvia V., et al.
Publicado: (2017)

The vascular clock system generates the intrinsic circadian rhythm of vascular contractility
por: Saito, Toshiro
Publicado: (2016)

An outbreak of infective endocarditis during the COVID-19 pandemic? - an observational retrospective single centre study
por: Cabral, M, et al.
Publicado: (2021)

Shroom2 regulates contractility to control endothelial morphogenesis
por: Farber, Matthew J., et al.
Publicado: (2011)

Generating fast-twitch myotubes in vitro with an optogenetic-based, quantitative contractility assay
por: Hennig, Katharina, et al.
Publicado: (2023)

Characterization of Contractile Machinery of Vascular Smooth Muscles in Hypertension
por: Yang, Qunhui, et al.
Publicado: (2021)

Development and in vivo validation of tissue-engineered, small-diameter vascular grafts from decellularized aortae of fetal pigs and canine vascular endothelial cells
por: Ma, Xu, et al.
Publicado: (2017)

Increased contractile responses to 5-hydroxytryptamine and Angiotensin II in high fat diet fed rat thoracic aorta
por: Ghatta, Srinivas, et al.
Publicado: (2004)

Contractile Force Is Enhanced in Aortas from Pendrin Null Mice Due to Stimulation of Angiotensin II-Dependent Signaling
por: Sutliff, Roy L., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_dp31bk671q9hlchtlcd1kq4kpi