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Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome

Obstructive sleep apnea syndrome (OSAS) is underdiagnosed in females and gender differences in clinical and polysomnographic findings have not been widely investigated in China. We examined clinical and polysomnographic differences between males and females with OSAS in order to determine the influe...

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Autores principales: Zhou, Xiaobo, Zhou, Bo, Li, Zhe, Lu, Qiao, Li, Shaoping, Pu, Zhongyin, Luo, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960714/
https://www.ncbi.nlm.nih.gov/pubmed/33723369
http://dx.doi.org/10.1038/s41598-021-85558-y
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author Zhou, Xiaobo
Zhou, Bo
Li, Zhe
Lu, Qiao
Li, Shaoping
Pu, Zhongyin
Luo, Fang
author_facet Zhou, Xiaobo
Zhou, Bo
Li, Zhe
Lu, Qiao
Li, Shaoping
Pu, Zhongyin
Luo, Fang
author_sort Zhou, Xiaobo
collection PubMed
description Obstructive sleep apnea syndrome (OSAS) is underdiagnosed in females and gender differences in clinical and polysomnographic findings have not been widely investigated in China. We examined clinical and polysomnographic differences between males and females with OSAS in order to determine the influence of gender on clinical presentation and polysomnographic features. Data were collected from 303 adult patients diagnosed with OSAS (237 males and 66 females) from 2017 to 2019. All the patients completed physical examination, Epworth sleepiness scale, and whole night polysomnography. AVONA, univariate and multivariate logistic regression analyses were conducted to assess gender differences of clinical and polysomnographic findings with OSAS. P < 0.05 was statistically significant. The average age was 48.4 ± 12.6 years for females and 43.4 ± 12.4 years for males. Compared with female patients with OSAS, male patients were taller and heavier, had higher systolic blood pressure in the morning, shorter duration of slow wave sleep, more micro-arousal events, greater AHI, and more complex sleep apnea events. There are obvious gender differences of clinical and polysomnographic characteristics with OSAS. Understanding gender differences will contribute to better clinical recognition of OSAS in females as well as the provision of proper health care and therapeutic practice.
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spelling pubmed-79607142021-03-19 Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome Zhou, Xiaobo Zhou, Bo Li, Zhe Lu, Qiao Li, Shaoping Pu, Zhongyin Luo, Fang Sci Rep Article Obstructive sleep apnea syndrome (OSAS) is underdiagnosed in females and gender differences in clinical and polysomnographic findings have not been widely investigated in China. We examined clinical and polysomnographic differences between males and females with OSAS in order to determine the influence of gender on clinical presentation and polysomnographic features. Data were collected from 303 adult patients diagnosed with OSAS (237 males and 66 females) from 2017 to 2019. All the patients completed physical examination, Epworth sleepiness scale, and whole night polysomnography. AVONA, univariate and multivariate logistic regression analyses were conducted to assess gender differences of clinical and polysomnographic findings with OSAS. P < 0.05 was statistically significant. The average age was 48.4 ± 12.6 years for females and 43.4 ± 12.4 years for males. Compared with female patients with OSAS, male patients were taller and heavier, had higher systolic blood pressure in the morning, shorter duration of slow wave sleep, more micro-arousal events, greater AHI, and more complex sleep apnea events. There are obvious gender differences of clinical and polysomnographic characteristics with OSAS. Understanding gender differences will contribute to better clinical recognition of OSAS in females as well as the provision of proper health care and therapeutic practice. Nature Publishing Group UK 2021-03-15 /pmc/articles/PMC7960714/ /pubmed/33723369 http://dx.doi.org/10.1038/s41598-021-85558-y Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zhou, Xiaobo
Zhou, Bo
Li, Zhe
Lu, Qiao
Li, Shaoping
Pu, Zhongyin
Luo, Fang
Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title_full Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title_fullStr Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title_full_unstemmed Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title_short Gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
title_sort gender differences of clinical and polysomnographic findings with obstructive sleep apnea syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960714/
https://www.ncbi.nlm.nih.gov/pubmed/33723369
http://dx.doi.org/10.1038/s41598-021-85558-y
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