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lncRNA Ttc3-209 Promotes the Apoptosis of Retinal Ganglion Cells in Retinal Ischemia Reperfusion Injury by Targeting the miR-484/Wnt8a Axis

PURPOSE: Apoptosis of the retinal ganglion cells (RGCs) can cause irreversible damage to visual function after retinal ischemia reperfusion injury (RIR). Using a lncRNA chip assay, we selected lncRNA Ttc-209 and characterized its role in RGCs during ischemia reperfusion (I/R)–induced apoptosis. METH...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Feng, Yuqing, Lu, Jinfang, Ge, Yanni, Li, Huiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960841/
https://www.ncbi.nlm.nih.gov/pubmed/33687475
http://dx.doi.org/10.1167/iovs.62.3.13