Cargando…

Spliceosomal snRNA Epitranscriptomics

Small nuclear RNAs (snRNAs) are critical components of the spliceosome that catalyze the splicing of pre-mRNA. snRNAs are each complexed with many proteins to form RNA-protein complexes, termed as small nuclear ribonucleoproteins (snRNPs), in the cell nucleus. snRNPs participate in pre-mRNA splicing...

Descripción completa

Detalles Bibliográficos
Autores principales:	Morais, Pedro, Adachi, Hironori, Yu, Yi-Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7960923/ https://www.ncbi.nlm.nih.gov/pubmed/33737950 http://dx.doi.org/10.3389/fgene.2021.652129

Ejemplares similares

Human spliceosomal snRNA sequence variants generate variant spliceosomes
por: Mabin, Justin W., et al.
Publicado: (2021)

Developmental Analysis of Spliceosomal snRNA Isoform Expression
por: Lu, Zhipeng, et al.
Publicado: (2014)

Pseudouridine modification in Caenorhabditis elegans spliceosomal snRNAs: unique modifications are found in regions involved in snRNA-snRNA interactions
por: Patton, Jeffrey R, et al.
Publicado: (2005)

U5 snRNA Interactions With Exons Ensure Splicing Precision
por: Artemyeva-Isman, Olga V., et al.
Publicado: (2021)

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA
por: Spiller, Michael P., et al.
Publicado: (2007)

Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development
por: Cheng, Lin, et al.
Publicado: (2020)

The TOR signaling pathway regulates starvation-induced pseudouridylation of yeast U2 snRNA
por: Wu, Guowei, et al.
Publicado: (2016)

Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes
por: Chen, Weijun, et al.
Publicado: (2014)

Deficiency of the minor spliceosome component U4atac snRNA secondarily results in ciliary defects in human and zebrafish
por: Khatri, Deepak, et al.
Publicado: (2023)

Topology of the U12–U6(atac) snRNA Complex of the Minor Spliceosome and Binding by NTC-Related Protein RBM22
por: Ciavarella, Joanna, et al.
Publicado: (2020)

Editorial: RNA modifications and epitranscriptomics, Volume II
por: Chen, Kunqi, et al.
Publicado: (2023)

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing
por: McGrail, Joanne C., et al.
Publicado: (2009)

Hyperstable U1snRNA complementary to the K-ras transcripts induces cell death in pancreatic cancer cells
por: Kato, K, et al.
Publicado: (2002)

Chemical Synthesis of U1 snRNA Derivatives
por: Ohkubo, Akihiro, et al.
Publicado: (2013)

Stem–loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly
por: Sharma, Shalini, et al.
Publicado: (2014)

The hidden RNA code: implications of the RNA epitranscriptome in the context of viral infections
por: Ribeiro, Diana Roberta, et al.
Publicado: (2023)

Editorial: Computational Epitranscriptomics: Bioinformatic Approaches for the Analysis of RNA Modifications
por: Dassi, Erik, et al.
Publicado: (2020)

U7 snRNA: A tool for gene therapy
por: Gadgil, Ankur, et al.
Publicado: (2021)

Functionally important structural elements of U12 snRNA
por: Sikand, Kavleen, et al.
Publicado: (2011)

Conformational dynamics of stem II of the U2 snRNA
por: Rodgers, Margaret L., et al.
Publicado: (2016)

Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo
por: Zhao, Xinliang, et al.
Publicado: (2007)

Brain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients
por: Zhang, Jing-Qian, et al.
Publicado: (2022)

Cajal body surveillance of U snRNA export complex assembly
por: Suzuki, Tatsuya, et al.
Publicado: (2010)

A New Class of SINEs with snRNA Gene-Derived Heads
por: Kojima, Kenji K.
Publicado: (2015)

U6 snRNA Pseudogenes: Markers of Retrotransposition Dynamics in Mammals
por: Doucet, Aurélien J., et al.
Publicado: (2015)

Structural basis for specific recognition of pre-snRNA by Gemin5
por: Tang, Xuhua, et al.
Publicado: (2016)

The right pick: structural basis of snRNA selection by Gemin5
por: Wahl, Markus C., et al.
Publicado: (2016)

Crystal structures of U6 snRNA-specific terminal uridylyltransferase
por: Yamashita, Seisuke, et al.
Publicado: (2017)

Development of Engineered-U1 snRNA Therapies: Current Status
por: Gonçalves, Mariana, et al.
Publicado: (2023)

Mechanism of U6 snRNA oligouridylation by human TUT1
por: Yamashita, Seisuke, et al.
Publicado: (2023)

RNA-mediated interaction of Cajal bodies and U2 snRNA genes
por: Frey, Mark R., et al.
Publicado: (2001)

Regulation of expression of human RNA polymerase II-transcribed snRNA genes
por: Guiro, Joana, et al.
Publicado: (2017)

Changes in snoRNA and snRNA Abundance in the Human, Chimpanzee, Macaque, and Mouse Brain
por: Zhang, Bin, et al.
Publicado: (2016)

U4 snRNA nucleolar localization requires the NHPX/15.5-kD protein binding site but not Sm protein or U6 snRNA association
por: Gerbi, Susan A., et al.
Publicado: (2003)

Gene expression profiling reveals U1 snRNA regulates cancer gene expression
por: Cheng, Zhi, et al.
Publicado: (2017)

SnRNA-Seq of Pancreas Revealed the Dysfunction of Endocrine and Exocrine Cells in Transgenic Pigs with Prediabetes
por: Peng, Huanqi, et al.
Publicado: (2023)

Mechanism of selective recruitment of RNA polymerases II and III to snRNA gene promoters
por: Dergai, Oleksandr, et al.
Publicado: (2018)

A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing
por: El Fatimy, Rachid, et al.
Publicado: (2022)

Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II
por: Rengachari, Srinivasan, et al.
Publicado: (2022)

Structure-function analysis of the 5′ end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors
por: Schwer, Beate, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_rgn5l1433ei9hgj87cjiq9gnd5